Difference between revisions of "APTX 4869"
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== Speculation == | == Speculation == | ||
===Immortality/anti-aging=== | ===Immortality/anti-aging=== | ||
| − | One possibility is that the goal of the APTX 4869 is to develop a therapy which will cause immortality or stall the effects of aging. | + | One possibility is that the goal of the APTX 4869 is to develop a therapy which will cause immortality or stall the effects of aging. The anti-aging side-effects of APTX 4869 probably indicate the main intent of the drug's development. Supporting this is Ai’s line, "Kudo-kun? You would probably never even dream that you are already part of a project the Black Organization has been working on already for half a century."<ref>Manga Volume 19, File 9: Chapter 191: Episode 130-131</ref> According to Haibara’s description about APTX 4869<ref>Manga Volume 24, File 10</ref>, it alters [[wiki:telomerase|telomerase]], a component limiting the number of times a cell can divide and therefore its lifespan, and “the reproductive potential” of cells. |
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| − | The anti-aging side-effects of APTX 4869 probably indicate the main intent of the drug's development. Supporting this is Ai’s line, "Kudo-kun? You would probably never even dream that you are already part of a project the Black Organization has been working on already for half a century."<ref>Manga Volume 19, File 9: Chapter 191: Episode 130-131</ref> According to Haibara’s description about APTX 4869<ref>Manga Volume 24, File 10</ref>, it alters [[wiki:telomerase|telomerase]], a component limiting the number of times a cell can divide and therefore its lifespan, and “the reproductive potential” of cells. | ||
APTX 4869 is the only known intersection between Shinichi and the B.O. It probably was just a useful side effect that the current prototype kills while leaving no trace in the victim’s body, and was thus employed as a poison - a usage which Haibara detests.<ref>Manga Volume 18, File 9, pg 9</ref> APTX4869 was called the "''incomplete'' detective", which means its true purpose has not yet been achieved. After [[Pisco]] saw Haibara shrink back to her child form, he commented that he was impressed she had developed the drug to that point, implying that deaging is in the right direction.<ref>Manga Volume 24, File 11, pg 9</ref> [[Sharon Vineyard|Vermouth's]] perpetual youth and her playing the role of her own mother/daughter indicate likewise | APTX 4869 is the only known intersection between Shinichi and the B.O. It probably was just a useful side effect that the current prototype kills while leaving no trace in the victim’s body, and was thus employed as a poison - a usage which Haibara detests.<ref>Manga Volume 18, File 9, pg 9</ref> APTX4869 was called the "''incomplete'' detective", which means its true purpose has not yet been achieved. After [[Pisco]] saw Haibara shrink back to her child form, he commented that he was impressed she had developed the drug to that point, implying that deaging is in the right direction.<ref>Manga Volume 24, File 11, pg 9</ref> [[Sharon Vineyard|Vermouth's]] perpetual youth and her playing the role of her own mother/daughter indicate likewise | ||
Revision as of 11:00, 15 February 2011
APTX 4869 (四八六九 Yon-Hachi-Roku-Kyuu), code-named Prototype Detective, is a fictional toxin and derivative of an experimental formula of unknown purpose developed by Shiho Miyano, which is used by the Black Organization as an untraceable, lethal poison.
APTX is an abbreviation of "Apoptoxin," and, as the name implies, it involves the activation of uncontrolled apoptosis which causes death by the destruction of cells. In addition, it can also activate telomerase. The original purpose of the compound, as hinted by Haibara herself, is "to raise the dead", indicating an intent to control biological life.[1]
However, in very rare cases, it causes the apoptosis of non-neural cells only and the apoptosis would stabilize at some point, causing the victim's apparent age to be decreased. Shinichi, the series' protagonist, is such a victim; later Shiho Miyano, who chooses to attempt suicide by using her own drug, was added to the two known people to have survive after taking the APTX-4869 throughout the series.
Reversing the effects
Throughout the series there are several instances in which the APTX was temporarily neutralized and Shinichi and Shiho were returned to their actual age forms. The main ingredient for this reversal is a component found in baijiu, which Ai has already incorporated in a prototype antidote for the APTX.[2]
It is to note that in the instances where Shinichi or Shiho were successfully changed back, the recipient was suffering from a common cold while the component was ingested, indicating that the immune system somehow has to be taxed for the antidote to work.[3][4][5] While not canon, Crossroad in the Ancient Capital uses this idea as Conan is given a pill to give him the symptoms of a cold, while drinking baijiu.
Though no explanation was given, Conan and Haibara briefly reverted to their true age while having rum cake in the non-canon live action Shinichi Kudo Returns! Confrontation with the Black Organization.
Speculation
Immortality/anti-aging
One possibility is that the goal of the APTX 4869 is to develop a therapy which will cause immortality or stall the effects of aging. The anti-aging side-effects of APTX 4869 probably indicate the main intent of the drug's development. Supporting this is Ai’s line, "Kudo-kun? You would probably never even dream that you are already part of a project the Black Organization has been working on already for half a century."[6] According to Haibara’s description about APTX 4869[7], it alters telomerase, a component limiting the number of times a cell can divide and therefore its lifespan, and “the reproductive potential” of cells.
APTX 4869 is the only known intersection between Shinichi and the B.O. It probably was just a useful side effect that the current prototype kills while leaving no trace in the victim’s body, and was thus employed as a poison - a usage which Haibara detests.[8] APTX4869 was called the "incomplete detective", which means its true purpose has not yet been achieved. After Pisco saw Haibara shrink back to her child form, he commented that he was impressed she had developed the drug to that point, implying that deaging is in the right direction.[9] Vermouth's perpetual youth and her playing the role of her own mother/daughter indicate likewise
References
- ^ Manga Chapter 384: The Unexpected Treasure
- ^ Manga Chapters 092-095: The Great Detective of the West
- ^ Manga Chapters 092-095: The Great Detective of the West
- ^ Manga Chapter 241: The Bullet from the Past
- ^ Manga Chapters 255-257: The School Play Case
- ^ Manga Volume 19, File 9: Chapter 191: Episode 130-131
- ^ Manga Volume 24, File 10
- ^ Manga Volume 18, File 9, pg 9
- ^ Manga Volume 24, File 11, pg 9
