APTX 4869

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Revision as of 10:57, 27 March 2010 by 134.93.147.11 (talk) (Reversing the effects)
APTX 4869

APTX 4869 (四八六九 Yon-Hachi-Roku-Kyuu?), code named Prototype Detective, is a fictional toxin is a derivative of an experimental immortality formula developed by Shiho Miyano, which is used by the Black Organization as an untraceable, lethal poison. APTX is an abbreviation of "Apoptoxin," and, as the name implies, it involves the activation of uncontrolled apoptosis which causes death by the destruction of cells. In addition, it can also activate telomerase.

However, in very rare cases, it causes the apoptosis of non-neural cells only and the apoptosis would stabilize at some point, causing the victim's apparent age to be decreased. Shinichi, the series' protagonist, is such a victim; later Shiho Miyano, who chooses to attempt suicide by using her own drug, was added to the two known people to have survive after taking the APTX-4869 throughout the series.

Reversing the effects

Gin poisons Shinichi

Throughout the series there are several instances in which the APTX was temporarily neutralized and Shinichi and Shiho were returned to their actual age forms. The main ingredient for this reversal is a component found in Chinese ginseng root schnaps, which Ai has already incorporated in a prototype antidote for the APTX.[1]

It is to note that in the instances where Shinichi or Shiho were successfully changed back, the recipient was suffering from a common cold while the component was ingested, indicating that the immune system somehow has to be taxed for the antidote to work.[2][3][4] While not canon, Crossroad in the Ancient Capital uses this idea as Conan is given a pill to give him the symptoms of a cold, while drinking Baigar.

Black Organization
High ranking The BossRumGinVermouth
Other agents VodkaKir (undercover) • ChiantiKornBourbon (undercover)
Deceased agents Akemi MiyanoTequilaKenzo Masuyama/PiscoAtsushi MiyanoElena MiyanoCalvadosRikumichi KusudaEthan Hondou (undercover) • Hiromitsu Morofushi/Scotch (undercover)
Former agents Shiho Miyano/Sherry (Ai Haibara) • Shuichi Akai/Dai Moroboshi/Rye (undercover) • Ki'ichiro Numabuchi
Extended canon Yoshiaki Hara (movie only) • Irish (movie only) • Masaaki Okakura (movie only) • Arrack (special manga only) • Generic (special manga only) • Blackbeard (special manga only) • Kate Lauren (playstation only) • Curaçao (movie only) • Stout (movie only) • Aquavit (movie only) • Leona Bucholz/Riesling (movie only) • Man in bar (tv special only) • Pinga (movie only)
Related articles Black Organization timelineAPTX 4869Nanatsu no KoScar AkaiList of Black Organization related charactersVermouth timelineSuguru ItakuraKohji Haneda caseKarasuma Group"The Criminal"Night BaronCrow
Manga Roller Coaster Murder Case¥1,000,000,000 RobberyBullet-Train BombingGame Convention CaseMissing Older Brother CaseMurdered Professor CaseHotel Party Murder CaseBus Hijacking CaseKaitou Kid and the MurderEscalator Message CaseGolden Apple CaseFootsteps of DarknessMeeting with VodkaFour Porsches CaseBathroom Murder CaseHalloween Party CaseBlack Organization vs. FBIMysterious Job CaseKir Transport CaseForeign Suspect CaseDepartment Store Bomber CaseOnline ClientMystery TrainTennis MeetupA Shrine to RememberElementary Teacher AssaultScarlet ShowdownGirls Band Murder CaseSoul Detective Murder CaseA song named ASACAMissing Maria Higashio CaseSisters' Birthday Party Murder CaseYusaku Kudo's TV Show CaseFBI Serial Murder CaseAkemi Miyano's Time CapsuleChess Tournament Murder Case
Anime Roller Coaster Murder CaseGame Company Murder CaseThe Black Organization: One Billion Yen Robbery CaseThe Girl from the Black Organization and the University Professor Murder CaseReunion with the Black OrganizationThe Gathering of the Detectives! Shinichi Kudo vs. Kaitou KidThe Mysterious PassengerThe Secret Rushed OmissionShinichi Kudo's New York CaseOn the Trail of a Silent WitnessContact with the Black OrganizationThe Four PorschesHidden Bathroom SecretHead-to-Head Match with the Black Organization: A Dual Mystery on a Full Moon NightBlack Impact! The Moment the Black Organization Reaches OutThe Shadow of the Black OrganizationClash of Red and BlackThe Crisis Beckoned by the Red OmenDetectives' NocturneThe Jet-Black Mystery TrainConan in a Locked RoomJodie's Memories and the Cherry Blossom Viewing TrapThe Scarlet ReturnThe Shadow Approaching Amuro (TV original) • The Unfriendly Girls BandThe Spirit Detective's MurderThe Betrayal's StageSearch for Maria-chan!The Birthday Party of Divine PunishmentYusaku Kudo's Detective ShowThe Black Organization's SchemeAkemi Miyano's Time Capsule
Movies and Specials Countdown to HeavenTime Travel of the Silver SkyBlack HistoryThe Raven ChaserShinichi Kudo Returns! Confrontation with the Black OrganizationThe Darkest NightmareBlack Iron Submarine
Special Manga The Wish Put on the AirshipThe Black Organization...RevealedProtect the Luxury Liner from the Virus
Playstation Remembrance Treasure Case
  1. ^ Manga Chapters 092-095: The Great Detective of the West
  2. ^ Manga Chapters 092-095: The Great Detective of the West
  3. ^ Manga Chapter 241: The Bullet from the Past
  4. ^ Manga Chapters 255-257: The School Play Case