Prototype antidote
Antidote (Prototype) is a type of antidote meant specially for Shinichi to revert the APTX 4869's body-reducing effects temporarily. It was created by Shiho Miyano, the original creator of the APTX 4869, who used baijiu (Chinese alcohol) as a main ingredient after Shinichi had told her about the baiju's effects.
Contents
Description
It is widely known that Shinichi has taken this antidote a number of times, usually twice every few hundred cases, occasionally that means, and the effects remain: back to Shinichi for 24 hours, return to Conan. Second dose: back to Shinichi for shortened time.
Many fans guess that this antidote made by Ai is not a prototype, but fully developed, with time limit side effects. This might be true, and the most likely reason she refrains from letting Shinichi take a lot or refrain from taking them herself is so they can stay away from the Black Organization until they find a way to liquidate the syndicate.
Main ingredients
Other than extracts of baijiu, not much is known about the antidote's ingredients. However, Shiho once mentioned about some parts of the APTX 4869 being added[citation needed], making the drug a very dangerous one if it were to be ingested for the very first time.
The known ingredients are:
- Baijiu enzyme extracts
- APTX 4869 powder extracts and parts[citation needed]
Usage
Dosages
According to Shiho, the first dosage will have its effects last for 24 hours, but the next dosage will be much shortened, due to the harmful chemicals in the antidote being recognised by Conan's immunity system. These two-dosage effects and side-effects stay consistent only if Conan takes them occasionally.
Ceasing effects
When the effects start to cease and Shinichi's about to turn back to Conan, he will feel intense heat, pain in chest, most likely because his bone, muscle and other cells are burning again. He will then turn back to a feverish and perspiring Conan, and will feel uncomfortable plus a bit unwell.
Dosages and ingestions
First time
When Ran had caught on to Shinichi's Conan identity secret, he had to find a way to make her think otherwise. Just as he was contemplating on confessing his true identity to Ran in a room, Ai comes in and convinces him confessing is dangerous.
Thus, Shiho (as Ai Haibara) helped him by coming up with an antidote, saying he had to take it at his own risk, because no one had tried it before - and hence he became the successful guinea pig. Ai went even further to dress up as Conan to appear at the same time with Shinichi, and Ran stopped suspecting him.[1][2]
Second time
The antidote prototype was again taken, this time accidentally in place of cough syrup. Luckily so, it seemed, because it was during a case where an enemy, in plastic surgery disguise as Shinichi, tried to implicate Shinichi. And since he had taken the drug, he could defend himself. It wore off 24 hours later, with Ai giving him another one to protect his identity. This time it wore off in a shortened 4 hours, once again interrupting the process of confession of feelings to Ran. The phrase of "It's always so close!" (which Gosho Aoyama uses quite frequently in love plots) can be read in the manga when he returns to his kiddo form of Conan.[3][4][5][6]
Holmes' Revelation
Most recently, in London, Conan is given the antidote so he can fly to London, because the alias Conan Edogawa does not exist and has no passport.
Haibara passes to Conan a second pill for the trip back to Japan. However, after Conan accidentally reveals Shinichi is in London, Shinichi (as Conan) is chased by Ran, who doesn't know she is actually chasing Conan, but thinks it's Shinichi she chased. Conan hides in the booth and ingests the return-trip pill, and walks out of the booth. A bawling Ran runs away, and Shinichi runs after her. He grabs her arm and pulls her in front of him at the Big Ben, and this time nothing stopped him from confessing his feelings, somehow.
Fortunately for Shinichi, after he turns back to Conan and apprehends the terrorist together with Minerva Glass, his parents Yusaku and Yukiko appear, giving him the third pill under orders from Haibara. He then goes back to Japan.[7][8][9]
Escape from a burning shack
Shiho takes her first temporary antidote to break down the door or a burning shack to free herself and the Detective Boys.
Other times
Haibara, due to not having a proper lab[10] and massive supply of ingredients, cannot mass produce the antidote.
In most movies, taking the antidote will last the normal form of Shinichi for only half, one or two hours,[11] and the one he took in OVA 9 made him fall into a coma, where he dreamt of him never being able to become Shinichi again, but remained Conan throughout ten years. When he woke up, he transformed back to Conan.[12]
Quotes
Taking one too many will thus render it (the pill) useless. — Ai Haibara, convincing Conan
He'll probably use one for Ran, so... — Ai Haibara, telling Shinichi's parents to bring a third pill to London
See also
References
- ^ Volume 26, Files 255-260
- ^ Episodes 188-193: The Desperate Revival
- ^ Volumes 62 & 63: Files 646-654
- ^ Episode 521
- ^ Episode 522
- ^ Episode 523
- ^ Episode 616-621
- ^ Volume 71, Files 743-751
- ^ Volume 72, File 752
- ^ Agasa's house
- ^ Movie, No. 7: Crossroad in the Ancient Capital
- ^ OVA, No. 9: The Stranger from Ten Years Later
- ^ Volume 26
